Science Meets Nutrition
NanoMD® Bright was developed by a multi-disciplinary team of world-class researchers and developers. It utilizes nanotechnologies that radically improve the bioavailability of chemical compounds used in pharmaceuticals & nutraceuticals. NanoMD® Bright contains patented ingredients. Use of the product is protected by one or more U.S. and other international patents.
Novel Supplement with Phenolic Compounds for Treatment of Melasma: Double Blind Placebo Controlled Trial Safety and Efficacy Evaluation, Corresponding Author: Downie, J. B., MD, FAAD, Image Dermatology, Montclair, NJ, USA; Journal: Dermatology and Dermatologic Diseases, 5(1).; Copyright: © 2018 Downie J, et al.
Background: Melasma is a chronic skin problem that causes dark, discolored patches on the skin and therefore can have adverse effects on quality of life. Recently, a novel complex was shown to decrease melasma. Specifically, the goal of the study was to prove that the formula can reduce melasma, overall hyperpigmentation and nontransient erythema.
Methods: Forty subjects with Fitzpatrick skin types III-V were enrolled in the double-blinded, randomized, placebo controlled trial: 20 were treated over 90 days with the oral supplement and 20 received a placebo over 90 days. Subjects were assessed at onset and re-assessed at 60 and 90 days by the Modified Melasma Area and Severity Index (mMASI), photographic documentation, hyperpigmentation tool, erythema index and client satisfaction. Subjects used the product or a placebo (in tablet form) orally once a day.
mMASI - NanoMD
Conclusion: Consistent, statistically significant reductions in melasma, as measured by mMASI scores, overall hyperpigmentation and non-transient erythema scores were achieved while meeting patient expectations at the 90 day follow-up evaluation point when compared to placebo. Results from this clinical trial suggest that this oral supplement is an effective treatment for melasma and may provide an alternative treatment for overall hyperpigmentation and non-transient erythema, while meeting expectations of patients. The product was well tolerated, with no reports of adverse events or side effects.
Patients were surveyed, whether they would recommend treatment to a friend. Satisfaction values were collected. 80% of surveyed patients report they would recommend the treatment to a friend.
Satisfaction Values [%]
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